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This can make you tired or weak or give you muscle cramps or a headacheif you take it with caffeine.The research on this isn't exactly clear. In one meta-analysis, it showed no effect on endurance, and in a randomised-controlled trial, it was found to be the exact opposite. That study suggests you should probably not take caffeine from the morning until 11:30pm, and only really use caffeine in the evening, when it's still more effective.3. It makes you thirstyCaffeine has been known to be quite thirsty as well, but this is one area where you shouldn't be using it in large doses. A small study showed that caffeine intake was related to the rate of fluid intake – if you drink enough tea during a session, the extra caffeine in it will be more readily absorbed. However, for drinks with much higher caffeine content, like coffee and tea, it may be better to drink lots of water afterwards.You may also find that you get thirsty at bedtime, and this may be more common after extended exposure to caffeine. This is the feeling you get when your blood sugar hits a low point without food.4. It impairs your sense of smellCaffeine is known to cause you to lose sleep. It may also be bad for your sense of smell, or simply lead to nasal and nasal congestion, or even asthma. This is because caffeine can increase blood pressure, which can lead to increased heart rate, blood pressure, blood sugar, or muscle pain.5. It changes your brain chemistryCaffeine can slow down your heart rate by about 30 per cent, and that's when it works most effectively for you. But it has been shown to increase the effect size of your heart's electrical currents by around five times – and that can lead to cardiac arrhythmia, or irregular heartbeats.6. It can lead to sleepiness or headachesThe study in fact showed that caffeine alone can help you sleep better, but it also increased your risk of headaches. This means you shouldn't use caffeine when you need to be awake later in the day either – for instance, in an evening meeting if you're working late.However, it's still best not to mix caffeine with alcohol and/or tea or coffee. It can cause you to become hungover or upset, not to mention wake up in a bad mood and feel like you need a cup of tea to help you sleep.If you do use coffee and/orSimilar articles: